Codeine and promethazine is a mixture drugs utilised to treat cold or allergy symptoms like runny nose, sneezing, and cough.
When useful for an prolonged time, this medication might not do the job too and may have to have different dosing. Talk with your medical doctor if this medication stops Doing the job nicely.
If a person has overdosed and it has major signs like passing out or difficulties respiratory, call 911. In any other case, connect with a poison Manage Middle without delay.
Tend not to flush prescription drugs down the rest room or pour them into a drain Unless of course instructed to take action. Effectively discard this solution when it can be expired or not desired. Talk to your pharmacist or area waste disposal business.
Ailments OF USE: The data On this database is intended to dietary supplement, not substitute for, the knowledge and judgment of Health care pros. The data is not really meant to address all feasible takes advantage of, directions, precautions, drug interactions or adverse outcomes, nor must it be construed to indicate that use of a selected drug is safe, suitable or efficient to suit your needs or any individual else.
Codeine is without doubt one of the By natural means taking place phenanthrene alkaloids of opium derived from the opium poppy; it is assessed pharmacologically as being a narcotic analgesic.
Opioid drugs can sluggish or prevent your breathing, and Loss of life may well manifest. Anyone caring for you ought get more info to seek unexpected emergency healthcare consideration if you have slow breathing with extended pauses, blue colored lips, or For anyone who is not easy to awaken.
Carcinogenicity scientific tests had been executed with codeine. Two-year reports in F344/N rats and B6C3F1 mice were being carried out to evaluate the carcinogenic potential of codeine. No evidence of tumorigenicity was noticed in male and woman rats at codeine dietary doses as many as 70 and 80 mg/kg/day (somewhere around similar to 15 and 20 times, the MRHD over a mg/m2 basis, respectively).
Be sure you know the way to choose this product or service and what other medicine it is best to prevent using with it. See also Drug Interactions portion. Get professional medical enable without delay if any of those extremely serious Unwanted effects take place: slow/shallow respiratory, uncommon lightheadedness, severe drowsiness/dizziness, issue waking up.
Will not raise your dose or use this product additional normally or for for a longer time than prescribed. Your condition will never boost any quicker, plus your possibility of Unwanted side effects will increase.
Promethazine with Codeine Oral Option need to be made use of with warning in sufferers with bone-marrow depression. Leukopenia and agranulocytosis have already been noted, generally when promethazine is used in Affiliation with other acknowledged marrow-toxic brokers.
To lessen the chance of dizziness and lightheadedness, rise up gradually when climbing from the sitting or lying placement.
Hemodialysis is not routinely utilized to enhance the elimination of codeine or promethazine from the human body.
Promethazine is metabolized through the liver to many different inactive metabolites for example sulfoxides of promethazine, N-demethylpromethazine and various glucuronides.